D27Y (p.Asp27Tyr) variant of LPA (Apolipoprotein(a))
D27Y (p.Asp27Tyr) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D27Y (p.Asp27Tyr) variant details
- p.Asp27Tyr
- TOPMed rs1473113079
- gnomAD rs1473113079
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.08
- MetaLR 0.18
- MetaSVM -0.89
- CADD 23.90
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available