D221H (p.Asp221His) variant of LPA (Apolipoprotein(a))
D221H (p.Asp221His) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D221H (p.Asp221His) variant details
- p.Asp221His
- Ensembl rs1779835206
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.12
- MetaLR 0.20
- MetaSVM -0.96
- CADD 21.90
- PolyPhen-2 0.98
- SIFT 0.15
- Population evidence available
- Structural context available