C202Y (p.Cys202Tyr) variant of LPA (Apolipoprotein(a))
C202Y (p.Cys202Tyr) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
C202Y (p.Cys202Tyr) variant details
- p.Cys202Tyr
- gnomAD rs1441807701
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.43
- MetaLR 0.81
- MetaSVM 0.12
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00013)
- Structural context available