C191R (p.Cys191Arg) variant of LPA (Apolipoprotein(a))
C191R (p.Cys191Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
C191R (p.Cys191Arg) variant details
- p.Cys191Arg
- Ensembl rs1779837224
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.71
- MetaLR 0.97
- MetaSVM 1.04
- CADD 28.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.4e-05)
- Structural context available