A222P (p.Ala222Pro) variant of LPA (Apolipoprotein(a))
A222P (p.Ala222Pro) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A222P (p.Ala222Pro) variant details
- p.Ala222Pro
- Ensembl rs758985366
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -1.02
- CADD 6.00
- PolyPhen-2 0.99
- SIFT 0.28
- Most common in the REMAINING population (allele frequency 9.8e-05)
- Structural context available