A199S (p.Ala199Ser) variant of LPA (Apolipoprotein(a))
A199S (p.Ala199Ser) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A199S (p.Ala199Ser) variant details
- p.Ala199Ser
- 1000Genomes rs1672519011
- gnomAD rs1672519011
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.19
- MetaLR 0.08
- MetaSVM -1.03
- CADD 1.73
- SIFT 0.34
- Most common in the 1KG:LWK population (allele frequency 0.012)
- Structural context available