A199P (p.Ala199Pro) variant of LPA (Apolipoprotein(a))
A199P (p.Ala199Pro) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A199P (p.Ala199Pro) variant details
- p.Ala199Pro
- 1000Genomes rs1672519011
- gnomAD rs1672519011
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.24
- MetaLR 0.22
- MetaSVM -0.82
- CADD 5.77
- PolyPhen-2 1.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 2.6e-05)
- Structural context available