A198V (p.Ala198Val) variant of LPA (Apolipoprotein(a))
A198V (p.Ala198Val) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A198V (p.Ala198Val) variant details
- p.Ala198Val
- gnomAD rs1369435281
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.17
- MetaLR 0.10
- MetaSVM -1.01
- CADD 8.89
- PolyPhen-2 0.99
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 4e-06)
- Structural context available