A17V (p.Ala17Val) variant of LPA (Apolipoprotein(a))
A17V (p.Ala17Val) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A17V (p.Ala17Val) variant details
- p.Ala17Val
- TOPMed rs1403161561
- gnomAD rs1403161561
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.07
- MetaLR 0.29
- MetaSVM -0.68
- CADD 2.81
- PolyPhen-2 0.33
- SIFT 0.26
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available