A17G (p.Ala17Gly) variant of LPA (Apolipoprotein(a))
A17G (p.Ala17Gly) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A17G (p.Ala17Gly) variant details
- p.Ala17Gly
- TOPMed rs1403161561
- gnomAD rs1403161561
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.05
- MetaLR 0.23
- MetaSVM -0.82
- CADD 5.61
- PolyPhen-2 0.93
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available