A131S (p.Ala131Ser) variant of LPA (Apolipoprotein(a))
A131S (p.Ala131Ser) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A131S (p.Ala131Ser) variant details
- p.Ala131Ser
- gnomAD rs1257893331
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.18
- MetaLR 0.06
- MetaSVM -1.03
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.28
- Population evidence available
- Structural context available