Y64C (p.Tyr64Cys) variant of LOX (Protein-lysine 6-oxidase)
Y64C (p.Tyr64Cys) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
Y64C (p.Tyr64Cys) variant details
- p.Tyr64Cys
- ExAC rs775925854
- gnomAD rs775925854
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.30
- CADD 29.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.5e-05)
- Structural context available