W5R (p.Trp5Arg) variant of LOX (Protein-lysine 6-oxidase)
W5R (p.Trp5Arg) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
W5R (p.Trp5Arg) variant details
- p.Trp5Arg
- ExAC rs770959043
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.11
- CADD 22.90
- PolyPhen-2 0.02
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 4.8e-06)
- Structural context available