V7M (p.Val7Met) variant of LOX (Protein-lysine 6-oxidase)
V7M (p.Val7Met) in LOX (Protein-lysine 6-oxidase) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
V7M (p.Val7Met) variant details
- p.Val7Met
- NCI-TCGA Cosmic COSV9914
- cosmic curated COSV99140
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.02
- CADD 18.70
- PolyPhen-2 0.00
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available