T6I (p.Thr6Ile) variant of LOX (Protein-lysine 6-oxidase)
T6I (p.Thr6Ile) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T6I (p.Thr6Ile) variant details
- p.Thr6Ile
- ExAC rs747093212
- gnomAD rs747093212
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.05
- CADD 22.80
- PolyPhen-2 0.03
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available