R33P (p.Arg33Pro) variant of LOX (Protein-lysine 6-oxidase)
R33P (p.Arg33Pro) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R33P (p.Arg33Pro) variant details
- p.Arg33Pro
- TOPMed rs1301371175
- gnomAD rs1301371175
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.13
- CADD 24.20
- PolyPhen-2 0.77
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 3.2e-05)
- Structural context available