P12T (p.Pro12Thr) variant of LOX (Protein-lysine 6-oxidase)
P12T (p.Pro12Thr) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P12T (p.Pro12Thr) variant details
- p.Pro12Thr
- 1000Genomes rs529787826
- ExAC rs529787826
- gnomAD rs529787826
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.05
- CADD 19.00
- PolyPhen-2 0.00
- SIFT 0.57
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available