L60P (p.Leu60Pro) variant of LOX (Protein-lysine 6-oxidase)
L60P (p.Leu60Pro) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L60P (p.Leu60Pro) variant details
- p.Leu60Pro
- TOPMed rs1378790528
- gnomAD rs1378790528
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.02
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the East Asian population (allele frequency 0.0002)
- Structural context available