L13W (p.Leu13Trp) variant of LOX (Protein-lysine 6-oxidase)
L13W (p.Leu13Trp) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L13W (p.Leu13Trp) variant details
- p.Leu13Trp
- Ensembl rs1754692774
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.10
- CADD 24.80
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the South Asian population (allele frequency 4.7e-05)
- Structural context available