A74V (p.Ala74Val) variant of LOX (Protein-lysine 6-oxidase)
A74V (p.Ala74Val) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A74V (p.Ala74Val) variant details
- p.Ala74Val
- gnomAD rs1754684821
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.04
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available