A4T (p.Ala4Thr) variant of LOX (Protein-lysine 6-oxidase)
A4T (p.Ala4Thr) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A4T (p.Ala4Thr) variant details
- p.Ala4Thr
- TOPMed rs1580568790
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.04
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the REMAINING population (allele frequency 1.9e-05)
- Structural context available