A41T (p.Ala41Thr) variant of LOX (Protein-lysine 6-oxidase)
A41T (p.Ala41Thr) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A41T (p.Ala41Thr) variant details
- p.Ala41Thr
- cosmic curated COSV50236
- ExAC rs753665073
- gnomAD rs753665073
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.02
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available