A25V (p.Ala25Val) variant of LOX (Protein-lysine 6-oxidase)
A25V (p.Ala25Val) in LOX (Protein-lysine 6-oxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A25V (p.Ala25Val) variant details
- p.Ala25Val
- ESP rs375966549
- ExAC rs375966549
- TOPMed rs375966549
- gnomAD rs375966549
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.05
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available