p.Gln15 Ala16insGlu variant of LMNA (Prelamin-A/C)

Name: LMNA p.Gln15 Ala16insGlu variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-05-15
License: https://catvariant.com/terms-of-use

p.Gln15 Ala16insGlu in LMNA (Prelamin-A/C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.

p.Gln15 Ala16insGlu variant details

rs751431601
gnomAD 1-156114961-C-CAG
Inframe Insertion
Variant Prioritization Score for Impact Estimate 0.7
CADD 21.40
Most common in the HGDP:SARDINIAN population (allele frequency 0.056)
Structural context available
Literature evidence available