P4P (p.Pro4Pro) variant of LMNA (Prelamin-A/C)
P4P (p.Pro4Pro) in LMNA (Prelamin-A/C) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P4P (p.Pro4Pro) variant details
- p.Pro4Pro
- rs369823958
- gnomAD 1-156114930-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.458
- CADD 16.80
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available