P20P (p.Pro20Pro) variant of LMNA (Prelamin-A/C)
P20P (p.Pro20Pro) in LMNA (Prelamin-A/C) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
P20P (p.Pro20Pro) variant details
- p.Pro20Pro
- rs1572331889
- gnomAD 1-156114978-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.281
- CADD 14.80
- Most common in the HGDP:CAMBODIAN population (allele frequency 0.25)
- Structural context available
- Literature evidence available