Y15C (p.Tyr15Cys) variant of LEP (Leptin)
Y15C (p.Tyr15Cys) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
Y15C (p.Tyr15Cys) variant details
- p.Tyr15Cys
- ExAC rs760165439
- TOPMed rs760165439
- gnomAD rs760165439
- Missense
- Variant Prioritization Score for Impact Estimate 0.0907
- REVEL 0.12
- CADD 0.17
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available