W3* (p.Trp3Ter) variant of LEP (Leptin)
W3* (p.Trp3Ter) in LEP (Leptin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
W3* (p.Trp3Ter) variant details
- p.Trp3Ter
- gnomAD 7-128252027-G-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.273
- CADD 27.10
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available