V51I (p.Val51Ile) variant of LEP (Leptin)
V51I (p.Val51Ile) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V51I (p.Val51Ile) variant details
- p.Val51Ile
- TOPMed rs1287727753
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.10
- CADD 16.70
- PolyPhen-2 0.36
- SIFT 0.14
- Population evidence available
- Structural context available