V19D (p.Val19Asp) variant of LEP (Leptin)
V19D (p.Val19Asp) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
V19D (p.Val19Asp) variant details
- p.Val19Asp
- gnomAD 7-128252074-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.25
- CADD 6.70
- PolyPhen-2 0.04
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available