T71I (p.Thr71Ile) variant of LEP (Leptin)
T71I (p.Thr71Ile) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
T71I (p.Thr71Ile) variant details
- p.Thr71Ile
- gnomAD 7-128254471-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.18
- CADD 16.60
- PolyPhen-2 0.72
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available