T58T (p.Thr58Thr) variant of LEP (Leptin)
T58T (p.Thr58Thr) in LEP (Leptin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T58T (p.Thr58Thr) variant details
- p.Thr58Thr
- rs199647957
- gnomAD 7-128254433-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.081
- CADD 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available