T33I (p.Thr33Ile) variant of LEP (Leptin)
T33I (p.Thr33Ile) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T33I (p.Thr33Ile) variant details
- p.Thr33Ile
- ExAC rs752496962
- gnomAD rs752496962
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.26
- CADD 16.00
- PolyPhen-2 0.09
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available