S46S (p.Ser46Ser) variant of LEP (Leptin)
S46S (p.Ser46Ser) in LEP (Leptin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
S46S (p.Ser46Ser) variant details
- p.Ser46Ser
- rs746345055
- gnomAD 7-128252156-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.398
- CADD 6.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available