R92R (p.Arg92Arg) variant of LEP (Leptin)
R92R (p.Arg92Arg) in LEP (Leptin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
R92R (p.Arg92Arg) variant details
- p.Arg92Arg
- rs745576625
- gnomAD 7-128254533-A-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.166
- CADD 1.97
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available