Q84K (p.Gln84Lys) variant of LEP (Leptin)
Q84K (p.Gln84Lys) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
Q84K (p.Gln84Lys) variant details
- p.Gln84Lys
- gnomAD 7-128254509-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.17
- CADD 11.40
- PolyPhen-2 0.04
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available