Q25R (p.Gln25Arg) variant of LEP (Leptin)
Q25R (p.Gln25Arg) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
Q25R (p.Gln25Arg) variant details
- p.Gln25Arg
- gnomAD 7-128252092-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.14
- CADD 0.21
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available