Q25Q (p.Gln25Gln) variant of LEP (Leptin)
Q25Q (p.Gln25Gln) in LEP (Leptin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
Q25Q (p.Gln25Gln) variant details
- p.Gln25Gln
- rs13306517
- gnomAD 7-128252093-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0948
- CADD 2.00
- Most common in the 1KG:CDX population (allele frequency 0.12)
- Structural context available
- Cited in: Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA… (PMID 23026132)