P90T (p.Pro90Thr) variant of LEP (Leptin)
P90T (p.Pro90Thr) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P90T (p.Pro90Thr) variant details
- p.Pro90Thr
- ExAC rs780990529
- gnomAD rs780990529
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.12
- CADD 14.20
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available