N43S (p.Asn43Ser) variant of LEP (Leptin)
N43S (p.Asn43Ser) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
N43S (p.Asn43Ser) variant details
- p.Asn43Ser
- TOPMed rs201494642
- Missense
- Variant Prioritization Score for Impact Estimate 0.081
- REVEL 0.10
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available