M89V (p.Met89Val) variant of LEP (Leptin)
M89V (p.Met89Val) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
M89V (p.Met89Val) variant details
- p.Met89Val
- gnomAD rs1231681476
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.09
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available