K74M (p.Lys74Met) variant of LEP (Leptin)
K74M (p.Lys74Met) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
K74M (p.Lys74Met) variant details
- p.Lys74Met
- gnomAD 7-128254480-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.12
- CADD 13.00
- PolyPhen-2 0.06
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available