K26E (p.Lys26Glu) variant of LEP (Leptin)
K26E (p.Lys26Glu) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
K26E (p.Lys26Glu) variant details
- p.Lys26Glu
- gnomAD rs1795281758
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.32
- CADD 21.40
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available