I38T (p.Ile38Thr) variant of LEP (Leptin)
I38T (p.Ile38Thr) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
I38T (p.Ile38Thr) variant details
- p.Ile38Thr
- Ensembl rs1795282176
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.61
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available