F17L (p.Phe17Leu) variant of LEP (Leptin)
F17L (p.Phe17Leu) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F17L (p.Phe17Leu) variant details
- p.Phe17Leu
- Ensembl rs201067336
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.03
- CADD 5.88
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available