C7G (p.Cys7Gly) variant of LEP (Leptin)
C7G (p.Cys7Gly) in LEP (Leptin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
C7G (p.Cys7Gly) variant details
- p.Cys7Gly
- gnomAD 7-128252037-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.42
- CADD 22.40
- PolyPhen-2 0.19
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available