P12P (p.Pro12Pro) variant of LDB3 (LIM domain-binding protein 3)
P12P (p.Pro12Pro) in LDB3 (LIM domain-binding protein 3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P12P (p.Pro12Pro) variant details
- p.Pro12Pro
- rs1564626136
- gnomAD 10-86668727-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.579
- CADD 14.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- LDB3 PDZ domain domainome 1.0: score -0.307
- Literature evidence available