G20G (p.Gly20Gly) variant of LDB3 (LIM domain-binding protein 3)
G20G (p.Gly20Gly) in LDB3 (LIM domain-binding protein 3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G20G (p.Gly20Gly) variant details
- p.Gly20Gly
- gnomAD 10-86668751-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.474
- CADD 17.90
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- LDB3 PDZ domain domainome 1.0: score -0.813
- Literature evidence available