S86Y (p.Ser86Tyr) variant of LBR (Delta(14)-sterol reductase LBR)
S86Y (p.Ser86Tyr) in LBR (Delta(14)-sterol reductase LBR) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
S86Y (p.Ser86Tyr) variant details
- p.Ser86Tyr
- Ensembl rs2096128678
- Missense
- Variant Prioritization Score for Impact Estimate 0.691
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.68
- CADD 26.30
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available