W33* (p.Trp33Ter) variant of LAG3 (P18627)
W33* (p.Trp33Ter) in LAG3 (P18627) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
W33* (p.Trp33Ter) variant details
- p.Trp33Ter
- NCI-TCGA Cosmic COSV9917
- cosmic curated COSV99179
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.853
- CADD 37.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available